This blog post on the *n*x blog gives a great description of how to install perl with threading, something that you need to do if you want to run padre.

The only thing I’d add that you can use the –as to install perl with an alias. This is useful if you want to build a threaded version of a perl you already have installed. You can simply do,

perlbrew install perl-5.14.2 -Dusethreads -Duselargefiles -Dcccdlflags=-fPIC -Doptimize=-O2 -Duseshrplib -Duse64bitall -Darchname=x86_64-linux-gnu -Dccflags=-DDEBIAN --as threaded-perl-5.14.2

(Note that I’ve customised this for my Ubuntu 64 bit os).